The thiolated chitosan: Synthesis, gelling and antibacterial capability.
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ID: 19890
2019
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Abstract
Chitosan-1-(mercaptomethyl)-cyclopropane acetic acid (CS-MCA) copolymer was synthesized by amino linkage. The obtained copolymer was characterized by FTIR, H NMR, XRD, TGA and SEM. Porous and reticulate morphologies were found on the CS-MCA surface. The effects of pH on the rheological properties of CS-MCA were investigated. On the one hand, the apparent viscosity of CS-MCA indicated a shear-thinning behavior. The graft of MCA enhanced the moduli and the maximum elastic properties were observed at pH = 7.00. The addition of dithiothreitol reduced the viscosity and modulus of CS-MCA hydrogel, and the gelation time, temperature and frequency were obtained in dynamic oscillatory tests. The antibacterial effect of CS-MCA against E. coli was investigated for the inhibition zone and bacterial growth curve. These results showed that CS-MCA had better antibacterial ability than chitosan without modification. Therefore, the rheological behavior and functional activities can be applied for the hydrocolloid gels in food and pharmaceutical applications.
| Reference Key |
luo2019theinternational
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|---|---|
| Authors | Luo, Qiang;Han, Qianqian;Wang, Ying;Zhang, Hongmei;Fei, Zhenghao;Wang, Yanqing; |
| Journal | International journal of biological macromolecules |
| Year | 2019 |
| DOI |
S0141-8130(19)33369-0
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| URL | |
| Keywords | Keywords not found |
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