in vitro adherence of candida albicans isolated from patients with chronic periodontitis
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ID: 197594
2011
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Abstract
Adherence is considered an extremely important virulence factor in yeast. OBJECTIVE: The aim of this study was to analyze the adherence to epithelial cells of C. albicans isolated from patients with chronic periodontitis in comparison to healthy patients. MATERIAL AND METHODS: Candida albicans cells isolated from individuals with chronic periodontitis (n=25) and healthy controls (n=25) were included in this study. Suspensions of C. albicans (10(6) cells/mL) and epithelial cells (10(5) cells/mL) were mixed and incubated at 37ºC for 1 h. The number of yeasts adhered to 25 epithelial cells was counted. RESULTS: The number of C. albicans cells adhered to epithelial cells was statistically higher in the chronic periodontitis group than in the control group (Student's t-test, p=0.000). CONCLUSION:The results of the present study suggest a higher Candida adherence of samples isolated from patients with chronic periodontitis.
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machado2011journalin
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| Authors | ;Adriana Gadotti Machado;Edson Yukio Komiyama;Silvana Soléo Ferreira dos Santos;Antonio Olavo Cardoso Jorge;Fernanda Lourenção Brighenti;Cristiane Yumi Koga-Ito |
| Journal | journal of animal and plant sciences |
| Year | 2011 |
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