research on induced pluripotent stem cells and the application in ocular tissues

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ID: 194173
2015
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Abstract
Induced pluripotent stem cells (iPSCs) were firstly induced from mouse fibroblasts since 2006, and then the research on iPSCs had made great progress in the following years. iPSCs were established from different somatic cells through DNA, RNA, protein or small molecule pathways and transduction vehicles. With continuous improvement of technology on reprogramming, the induction of iPSCs became more secure and effective, and showed enormous promise for clinical applications. We reviewed different reprogramming of somatic cells, four kinds of pathways of reprogramming and three types of transduction vehicles, and discuss the research of iPSCs in ophthalmology and the prospect of iPSCs applications.
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guo2015internationalresearch Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Xiao-Ling Guo;Jian-Su Chen
Journal The Classical Review
Year 2015
DOI
10.3980/j.issn.2222-3959.2015.04.31
URL
http://www.ijo.cn/en_publish/2015/4/20150431.pdf
Keywords
induced pluripotent stem cells reprogramming

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