synthesis and reactivity of some mannich bases. viii. studies on several mannich bases derived from ortho-hidroxyacetophenones and their conversion into oximino derivatives

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ID: 194098
2001
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Abstract
The synthesis of several Mannich bases resulting from the reaction of 2-hydroxy-4-methylacetophenone with paraformaldehyde and secondary amines is reported. Another series of products was obtained from N,N-dimethyl substituted Mannich bases by replacing the amino group with pyrrolidine. Most of the Mannich bases were transformed into oximes by treatment with hydroxylamine hydrochloride in 10 % NaOH.
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Authors ;BOGDAN COMANITA;IRINA POPOVICI;EUGENIA COMANITA;GHEORGHE ROMAN
Journal meditsinskaia radiologiia
Year 2001
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