o papel do adesivo de fibrina e da sutura na fixação do transplante de menisco preservado por ultracongelamento em coelhos the role of fibrin glue and suture on the fixation of ultra frozen preserved meniscus transplantation in rabbits
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Abstract
OBJECTIVE: To evaluate the ability of fibrin adhesive in promoting the meniscus fixation within two, four and eight weeks compared to the conventional soft-tissue suture technique. MATERIALS AND METHODS: 36 right medial menisci of rabbits preserved at negative 73° Celsius for 30 days were transplanted to animals of the same sample and fixed with soft-tissue suture or fibrin glue. After 2, 4 or 8 weeks, the appearance of the menisci and the quality of fixation were macroscopically checked and evaluated by a scoring system. The findings were subjected to the statistical study of variance analysis (p < 0.05%). RESULTS: The deep-frozen meniscus preservation maintained the integrity of the meniscus transplant, and, macroscopically, there was no significant reduction of the length of the meniscus in all post-transplant periods (p = 0.015). The menisci fixed with fibrin showed slight changes in color and surface roughness. There were no signs of rejection or infection in both groups. Suture fixation scoring was superior (p = 0.015) in all periods (80% of total fixation) as compared to the setting promoted by fibrin (20% of total fixation). CONCLUSION: The homologous transplantation of the meniscus of rabbits experienced various degrees of integration to the knee according to the fixation method; the surgical soft tissues suturing technique was shown to be superior in the evaluation of scores compared to the fixation with fibrin adhesive.
| Reference Key |
reckers2009revistao
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| Authors | ;Leandro José Reckers;Djalma José Fagundes;José Luiz Pozo Raymundo;Geraldo Sérgio de Mello Granata Júnior;Márcia Bento Moreira;Vanessa Carla Paiva;Anna Luiza Negrini Fagundes;Moises Cohen |
| Journal | scientific american |
| Year | 2009 |
| DOI |
10.1590/S0102-36162009000500005
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| URL | |
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