pancreatic gist in a patient with limited stage small cell lung cancer: a case report and review of published cases

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ID: 192403
2016
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Abstract
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract and usually occur in the stomach and the small intestine. The pancreas is an extremely rare primary site for GISTs and there are 25 reported cases of pancreatic GIST with most being treated with surgical resection. We describe a 52-year-old African-American female who was diagnosed with limited stage small cell carcinoma in November 2009 and treated with concurrent cisplatin/etoposide chemotherapy and radiation. She subsequently achieved complete remission. Two years later she was diagnosed with localized pancreatic GIST by endoscopic ultrasonography guided fine needle aspiration. We treated her with a tyrosine kinase inhibitor (TKI) imatinib 400 mg oral dose daily as she declined surgery. Her disease is stable based on computed tomography imaging scans 40 months after diagnosis without any metastasis. To the best of our knowledge, our case is the second case of localized pancreatic GIST treated with TKI monotherapy.
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Authors ;Minh Phan;Shari Jones;Justin Jenkins;Shubham Pant;Mohamad Khawandanah
Journal aaps pharmscitech
Year 2016
DOI
10.1155/2016/9604982
URL
http://dx.doi.org/10.1155/2016/9604982
Keywords
neoplasms Oncology including cancer and carcinogens tumors

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