the effect of 12 weeks of submaximal swimming exercise on resting levels of vegf in rats exposed to nicotine-derived nitrosamine ketone

Clics: 223
ID: 191187
2018
PDF Gratuito
Metricas de Calidad y Rendimiento del Articulo
Calidad General
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
Evaluacion de Calidad por IA
No analizado
Readership in this journal
Emerging

Ranked #46 of 69 articles by views in journal of consulting and clinical psychology

Most read Least read

Bar heights use a square-root scale.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Resumen
Background and Objectives: Tobacco contains carcinogens, such as nitrosamine ketone (NNK), which play a role in induction of lung cancer through stimulation of vascular endothelial growth factor (VEGF) expression. The aim of this study was to investigate changes in resting levels of VEGF in lung tissues of rats exposed to nicotine-derived NNK following 12 weeks of aerobic submaximal swimming exercise.   Methods: In this experimental study, 46 mature Wistar rats, were randomly divided into five groups, including: exercise, exercise + NNK, NNK, solvent, and control. The groups induced by NNK, received NNK subcutaneously once per week at a rate of 12.5mg/kg body weight for 12 weeks. The training groups performed submaximal swimming exercise for 12 weeks. The levels of VEGF in homogenized lung tissue were measured by ELISA. Data analysis was performed using one-way ANOVA and Tukey's tests at a significance level of p≤0.05.   Results: In this study, a period of swimming training program significantly decreased the levels of VEGF in lung tissue compared to control (p=0.039) and NNK (p≤0.001) groups. A significant reduction was also observed in the VEGF level in exercise + NNK group compared to NNK group (p≤0.001). Furthermore, VEGF levels significantly increased in NNK group compared to exercise (p≤0.001), exercise+NNK (p≤0.001), and solvents (p≤0.001) groups.   Conclusion: Overall, it can be concluded that regular submaximal aerobic exercise plays an effective role in the inhibition of NNK-induced lung  
Clave de Referencia
barzegari2018majallah-ithe Use esta clave para autocitar en el manuscrito mientras usa SciMatic Manuscript Manager o Thesis Manager
Autores ;ali barzegari;shadmehr mirdar
Revista journal of consulting and clinical psychology
Ano 2018
DOI
DOI no encontrado
URL
http://journal.muq.ac.ir/browse.php?a_code=A-10-677-1&slc_lang=en&sid=1
Palabras Clave
Medicine (General) swimming vascular endothelial growth factor a

Citas

No se encontraron citas. Para agregar una cita, contacte al administrador en info@scimatic.org

Comentarios

Aun no hay comentarios. Sea el primero en comentar este articulo.