NMR based profiling of sesquiterpene lactones in Saussurea lappa roots collected from different location of Western Himalaya

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ID: 189349
2020
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Abstract
(Decne.) Sch.Bip is a well known herbal medicine has been extensively used for many therapeutic purposes. In this article, we have accomplished targeted profiling of roots samples collected from different locations (Pangi, Lahaul, Barot and Kullu) of the western Himalayan region using NMR. This study allowed us to assigned four major sesquiterpenes of this plant, including costunolide (CL), dehydrocostus lactone (DCL), alantolactone (AL), isoalantolactone (IAL). Quantification of sesquiterpene lactones have also been accomplished using HNMR, and a wide diversity in the concentration of these active metabolites was observed. It has been observed that AL and IAL were major in the samples collected from Lahaul and Barot regions, and CL and DCL were major in the samples collected from Kullu and Pangi regions. This study concludes that roots possess wide chemical diversity, which may be due to various biotic and abiotic environmental related factors.
Reference Key
kumar2020nmrnatural Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Kumar, A.
Journal Natural product research
Year 2020
DOI
10.1080/14786419.2020.1789635
URL
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