cd8+ t cells in leishmania infections: friends or foes?

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ID: 189113
2012
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Abstract
Host protection against several intracellular pathogens requires the induction of CD8+ T cell responses. CD8+ T cells are potent effector cells that can produce high amounts of pro-inflammatory cytokines and kill infected target cells efficiently. However, a protective role for CD8+ T cells during Leishmania infections is still controversial and largely depends on the infection model. In this review, we discuss the role of CD8+ T cells during various types Leishmania infections, following vaccination, and as potential immunotherapeutic targets.
Reference Key
estager2012frontierscd8+ Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Simona eStager;Sima eRafati
Journal sudebno-meditsinskaia ekspertiza
Year 2012
DOI
10.3389/fimmu.2012.00005
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