refractory gout attack

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ID: 188627
2012
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Ranked #230 of 309 articles by views in Frontiers in pharmacology

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Abstract
Refractory gout attack is an uncommon problem, since gout flares are usually self-limited. This clinical condition is characterized by serum uric acid higher than 6 mg/Dl or continuous manifestations of recurrent flares, chronic arthritis, and increased tophi. We report in this paper a 69-year-old man with a polyarticular and protracted gout attack, despite usual treatment and low urate sera levels. In order to manage this problem, we reviewed gout pathophysiology and developed a therapeutic solution based on benzbromarone pharmacokinetics. We also review herein new options for gout treatment that could be used in similar cases.
Reference Key
fargetti2012caserefractory Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Simone Fargetti;Claudia Goldenstein-Schainberg;Andressa Silva Abreu;Ricardo Fuller
Journal Frontiers in pharmacology
Year 2012
DOI
10.1155/2012/657694
URL
http://dx.doi.org/10.1155/2012/657694
Keywords
Medicine

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