3-year outcomes of endocardial implantation of autologous bone marrow mononuclear cells in cad patients with normal ejection fraction value
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2015
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Abstract
Objectives. 3-year research data on transendocardial implantation of autologous bone marrow mononuclear cells (ABMMC) in CAD patients with a preserved systolic function of the left ventricle (LV) were analyzed. Methods. The study included 30 patients with post-infarction cardiosclerosis, with their LV EF varying from 50 % to 70 %. To administer an average 41 16 x 10 6 dose of ABMMC into the myocardial infarction borderline, the NOGA system was used. Results. Lethality at 36 months was 6.6 % (2 patients) and both cases were not related to the main pathology. Within 36 months of ABMMC implantation, the functional class of angina improved from с 2.80.1 to 2.1 01 (р<0.05) and NYHA functional class decreased from 2.80.1 to 2.30.1 (p<0.05). After 36 postoperative months, in most patients the cumulative myocardial perfusion observed at 12 months remained the same in the ABMMC segments. Transendocardial implantation is a safe intervention that improves patients hemodynamic parameters and quality of life.
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| Reference Key |
2015patologi3-year
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|---|---|
| Authors | ;А. М. Чернявский;Е. Н. Кливер;Е. А. Покушалов;А. Б. Романов;И. Н. Терехов |
| Journal | iccea 2004 - 2004 3rd international conference on computational electromagnetics and its applications, proceedings |
| Year | 2015 |
| DOI |
10.21688/1681-3472-2015-1-59-65
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| URL | |
| Keywords | Keywords not found |
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