desnutrição e qualidade de vida em doentes com cancro do pulmão não pequenas células

Clicks: 52
ID: 187050
2011
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Abstract
Resumo: O cancro está associado a uma deterioração do estado nutricional e da qualidade de vida (QdV), mas não se conhece a dimensão destas consequências nos doentes com cancro do pulmão não pequenas células (CPNPC). O objectivo deste estudo foi avaliar a associação entre a qualidade de vida e a desnutrição em doentes com CPNPC. O estado nutricional foi avaliado pelo Patient Generated – Subjective Global Assessment e a QdV foi avaliada através do European Organization for Research and Treatment of Cancer Quality of Life – C30 e do módulo específico para doentes com cancro do pulmão. Foi avaliada uma amostra com cinquenta e seis doentes diagnosticados com CPNPC. Uma elevada proporção de doentes encontra-se desnutrida (35,7%), dos quais 1,8% em estadios precoces vs 33,9% em estadios avançados de doença. A desnutrição está associada a dimensões de QdV como a falta de apetite (rho = 0,70), fadiga (rho = 0,54), náuseas e vómitos (rho = 0,52) e também obstipação (rho = 0,56). Os doentes com CPNPC apresentam elevada frequência de desnutrição nos estadios avançados de doença. Os doentes desnutridos apresentam mais sintomatologia e piores estado de saúde global, de funcionamento físico, emocional, social e de desempenho, do que os doentes sem desnutrição. A desnutrição está associada com pior QdV, especificamente nos parâmetros: falta de apetite, náuseas e vómitos, obstipação e fadiga. Abstract: Cancer is related to a deterioration of nutritional status and quality of life (QoL), but the extent of these conditions in patients with Non Small Cell Lung Cancer (NSCLC) has not been studied. The aim of the present study was to assess the association between QoL and undernutrition in NSCLC patients. Nutritional status was evaluated with Patient Generated – Subjective Global Assessment and QoL using the European Organization for Research and Treatment of Cancer Quality of Life – C30 and also with the specific module for lung cancer patients. A consecutive sample of fifty six patients diagnosed with NSCLC was evaluated. A high proportion of patients is undernourished (35.7%), 1.8% in early stages vs 33.9% in advanced stages of disease. Undernutrition is related to measured dimensions of QoL: lack of appetite (rho = 0.70), fatigue (rho = 0.54), nausea and vomiting (rho = 0.52) and constipation (rho = 0.56). Undernourished patients have worse global health status, physical, emotional, social and role functioning.Patients with NSCLC have high frequency of undernutrition in advanced stages of disease. Undernourished patients present more symptoms, a worse global health status/QoL, physical, role, emotional and social functioning than patients without undernutrition. Undernutrition is associated with worse QoL, specifically in the parameters: appetite loss, nausea and vomiting, constipation and fatigue. Palavras-chave: Cancro do Pulmão Não Pequenas Células, Desnutrição, Qualidade de Vida, PG-SGA, Keywords: Non Small Cell Lung Cancer, Undernutrition, Quality of Life, PG-SGA
Reference Key
xar¡2011revistadesnutri§£o Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;S. Xará;T.F. Amaral;B. Parente
Journal the journal of applied psychology
Year 2011
DOI
DOI not found
URL
http://www.sciencedirect.com/science/article/pii/S0873215911000365
Keywords
diseases of the respiratory system

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