capacidade funcional máxima, fração de ejeção e classe funcional na cardiomiopatia chagásica: existe relação entre estes índices? maximal functional capacity, ejection fraction, and functional class in chagas cardiomyopathy: are these indices related?

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ID: 181977
2005
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Abstract
OBJETIVO: Avaliar a potencial associação entre a capacidade funcional máxima (VO2max), fração de ejeção do ventrículo esquerdo (FEVE) e a classe funcional (CF) pela NYHA em pacientes com cardiomiopatia chagásica. MÉTODOS: Foram estudados 104 homens, com idade média de 40.3± 9.0 anos (variação: de 18 a 65), com diagnóstico estabelecido de cardiomiopatia chagásica. A FEVE e VO2max foram classificadas em três categorias: FEVE <0.30, 0.30< FEVE <0.50, e FEVE > 0.50 e VO2max <10, 1020 ml.kg-1.min-1, respectivamente. RESULTADOS: Do total, 31 (29.8%) pacientes estavam em CF II, 41 (39.4%) em classe funcional III, e 32 (30.8%) em CF IV. Os valores correspondentes do VO2max e da FEVE para CF II, III e IV foram 21.5±4.0 ml.kg-1.min-1, 18.3±5.8 ml.kg-1.min-1 e 14.7±4.9 ml.kg-1.min-1 e 0.50±0.6, 0.35±0.9 e 0.29±0.7, respectivamente. FEVE <0.30 e VO2max <10 ml.kg-1.min-1 foram encontradas na grande maioria dos pacientes em CF IV. Inversamente, pacientes em CF II foram relacionados com FEVE >0.50 como também VO2max >20 ml.kg-1.min-1. CONCLUSÃO: Existe uma boa associação entre a classe funcional, a capacidade funcional máxima e a fração de ejeção do ventrículo esquerdo em pacientes com cardiomiopatia chagásica. Dados que podem ser úteis no manuseio da insuficiência cardíaca, em chagásicos.
OBJECTIVE: Left ventricular ejection fraction (LVEF) and maximal functional capacity (VO2max) have both been shown to be related to a poor long-term survival in Chagas' disease patients. The aim of this study was to estimate the potential association of VO2max, LVEF, and NYHA functional class in patients with Chagas' disease cardiomyopathy. METHODS: One hundred four male patients, aged 40.3±9.0 years (range, 18 to 65), with a definite diagnosis of Chagas disease cardiomyopathy were studied. LVEF and VO2max were both classified into 3 degrees: LVEF <0.30, 0.30< LVEF <0.50, and LVEF > 0.50 and VO2max <10, 1020 ml.kg-1.min-1, respectively. RESULTS: Thirty-one patients (29.8%) were in NYHA functional class II, 41 (39.4%) in functional class III, and 32 (30.8%) in functional class IV. The corresponding values of VO2max and LVEF for functional classes II, III, and IV were 21.5±4.0 ml.kg-1.min-1, 18.3±5.8 ml.kg-1.min-1, and 14.7±4.9 ml.kg-1.min-1 and 0.50±0.6, 0.35± 0.9, and 0.29±0.7, respectively. LVEF= <0.30 and VO2max = <10 ml.kg-1.min-1 were found in the majority of patients in NYHA functional class IV. Conversely, patients in functional class II were mostly those with LVEF >0.50 as well as VO2max >20 ml.kg-1.min-1. CONCLUSION: A convincingly good association exists between NYHA functional class, functional capacity and LVEF in patients with Chagas' disease cardiomyopathy. These data may be helpful in the management of heart failure in Chagas' disease patients.
Reference Key
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Authors ;Charles Mady;Vera Maria Cury Salemi;Barbara Maria Ianni;Felix José Alvarez Ramires;Edmundo Arteaga
Journal revista cubana de ciencias informáticas
Year 2005
DOI
10.1590/S0066-782X2005000200011
URL
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2005000200011
Keywords
ejection fraction

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