demonstration of antibody and cellular immune response to brain extract in west and lennox-gastaut syndromes

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ID: 181216
1984
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Abstract
We investigated humoral and cellular immune response to brain tissues in 15 patients with West syndrome, in 9 patients with Lennox-Gastaut syndrome and in 20 healthy children. High levels of a precipitating antibody to a saline extract of brain tissue were detected in all patients; leucocyte migration inhibition test with the same antigen was found to be positive in most of them. The role of this autoimmune response in the pathogenesis of West and Lennox-Gastaut syndromes remains to the elucidated.
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Authors ;Norma G. S. Mota;M. Thereza Rezkallah-Iwasso;M. Terezinha S. Peraçoli;Terezinha C. B. Montelli
Journal communications in computer and information science
Year 1984
DOI
10.1590/S0004-282X1984000200004
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