impact of 10-valent pneumococcal conjugate vaccine on pneumococcal meningitis in children up to two years of age in brazil
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ID: 175790
2015
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Abstract
The objective of this study was to analyze the impact of vaccination against Streptococcus pneumoniae on the morbidity and mortality from pneumococcal meningitis in children ≤ 2 years in Brazil, from 2007 to 2012. This is a descriptive study and ecological analysis using data from the Information System on Notifiable Diseases. Pre-vaccination (2007-2009) and post-vaccination (2011-2012) periods were defined to compare incidence rates and mortality. A total of 1,311 cases and 430 deaths were reported during the study period. Incidence decreased from 3.70/100,000 in 2007 to 1.84/100,000 in 2012, and mortality decreased from 1.30/100,000 to 0.40/100,000, or 50% and 69% respectively, with the greatest impact in the 6-11 month age group. This decrease in Pneumococcal meningitis morbidity and mortality rates two years after introduction of the 10-valent pneumococcal conjugate vaccine suggests its effectiveness.
| Reference Key |
grando2015cadernosimpact
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| Authors | ;Indianara Maria Grando;Camile de Moraes;Brendan Flannery;Walter Massa Ramalho;Marco Aurélio P. Horta;Diana Lucia Moura Pinho;Gilmara Lima Nascimento |
| Journal | iberian conference on information systems and technologies, cisti |
| Year | 2015 |
| DOI |
10.1590/0102-311X00169913
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