an alternative route for the synthesis of (e)-(+)-5(s)-methylhept-2-en-4-one (filbertone)
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ID: 174614
1998
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Abstract
We are reporting an alternative methodology to prepare (+)-Filbertone (1), a natural flavor isolated from hazelnut extracts. Commercially available (-)-2(S)-methylbutan-1-ol (2) was used as starting material and the synthesis was carried out in four steps with an overall yield of 42%. The optical rotation and the enantiomeric purity of the final compound were determined.
| Reference Key |
h.g.1998journalan
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|---|---|
| Authors | ;Zarbin Paulo H.G.;Yonashiro Massami;Perissini Jr Waldir |
| Journal | british journal of dermatology |
| Year | 1998 |
| DOI |
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| Keywords | Keywords not found |
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