Obesity related lung complications and a possible phytochemical therapeutic solution.

Clicks: 82
ID: 171875
2020
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Emerging

Ranked #59 of 67 articles by views in jpma the journal of the pakistan medical association

Most read Least read

Bar heights use a square-root scale.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
Proteases, especially neutrophil elastase (NE), enzyme provide innate immunity in the lung tissues against elastin protein disintegration by microbial attacks. Normally, an antiprotease, called alpha-1-antitrypsin (A1AT), is responsible to keep NE activity in normal range. In most of the leptin-resistant obese subjects, A1AT deficiency develops which leads to a concurrent higher activity of NE. Obesity associated antiprotease-protease imbalance induces various lung complications, i.e. asthma, emphysema, chronic obstructive pulmonary disorders (COPD), cancer, etc. Past studies manifested that plant extracts/compounds reduce human NE activity. This knowledge will help in future to exploit phytochemicals as interventional therapeutic agents to decrease NE over-activity in susceptible obese individuals. Furthermore, the hypothesis discussed in this article will be helpful for researchers working in the fields of lung biology and obesity.
Reference Key
khawaja2020obesityjpma Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Khawaja, Sundus;Khan, Abdul Rehman;
Journal jpma the journal of the pakistan medical association
Year 2020
DOI
DOI not found
URL URL not found
Keywords
obesity; lung complications; phytochemicals.

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.