is cold the new hot in sudden unexpected death in epilepsy? effect of low temperature on heart rate of rats with epilepsy É o frio responsável por mortes inesperadas em epilepsia? efeito de temperaturas baixas na frequência cardíaca de ratos com epilepsia

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ID: 170453
2008
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Abstract
Sudden unexpected death in epilepsy (SUDEP) is the commonest cause of seizure-related mortality in people with refractory epilepsy. Several risk factors for SUDEP are described; however, the importance of including low temperatures as risk factor for SUDEP was never explored. Based on this, the aim of this study was to evaluate the heart rate of rats with epilepsy during low temperature exposure. Our results showed that low temperature clearly increased the heart rate of rats with epilepsy. Taken together, we concluded that exposure to low temperatures could be considered important risk factors from cardiovascular abnormalities and hence sudden cardiac death in epilepsy.
A morte súbita e inesperada nas epilepsias (SUDEP) é considerada a maior causa de morte em indivíduos com epilepsia refratária. Vários fatores de risco para SUDEP têm sido descritos, no entanto, a inclusão das baixas temperaturas como um possível fator de risco para SUDEP não foi verificada até o momento. Nesse sentido, o objetivo desse estudo foi verificar a freqüência cardíaca de animais com epilepsia expostos as temperaturas baixas. Nossos resultados demonstraram que as baixas temperaturas são capazes de aumentar significativamente a freqüência cardíaca de animais com epilepsia. Dessa forma, concluímos que as baixas temperaturas podem ser consideradas um importante fator de risco de possíveis alterações cardiovasculares e até mesmo morte súbita cardíaca nas epilepsias.
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sonoda2008arquivosis Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Eliza Y.F. Sonoda;Diego B. Colugnati;Carla A. Scorza;Ricardo M. Arida;Aline P. Pansani;Antonio-Carlos G. de Almeida;Esper A. Cavalheiro;Fulvio A. Scorza
Journal communications in computer and information science
Year 2008
DOI
10.1590/S0004-282X2008000600014
URL
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2008000600014
Keywords
epilepsy seizure low temperatures neuropsychiatry biological psychiatry heartneurosciences

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