study of aetiology and outcome in acute febrile illness patients with multiple organ dysfunction syndrome
Clicks: 276
ID: 170023
2016
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This
article has not been analysed, so there is no overall score —
reader engagement is measured and shown alongside.
Reader Engagement
Popular Article
30.0
/100
276 views
42 readers
AI Quality Assessment
Not analyzed
Readership in this journal
PopularRanked #36 of 86 articles by views in JAMA network open
Most read
Least read
Bar heights use a square-root scale.
Mint this article as an NFT
Not yet mintedCreate a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.
5
SUSD
one-off · no wallet required
Abstract
Introduction: Acute febrile illness with Multi Organ Dysfunction
Syndrome (MODS) carries significant morbidity and mortality
despite standard therapy in intensive care settings. Infections
are the most common cause of MODS followed by polytrauma.
Present study was undertaken in medical intensive care units of
a tertiary hospital to study the aetiology and outcome among
patients with acute febrile illness developing MODS.
Aim: 1) To study the aetiology of acute febrile illness in patients
developing MODS.
2) To study the final outcome among these patients.
Materials and Methods: The present study was conducted
at a tertiary care hospital in Mysuru, Karnataka, India, over a
period of 6 months from July 2013 to December 2013. The
Institutional Ethics Committee Approval (IEC) was obtained
before the commencement of the study. A total of 213 cases
admitted in intensive care unit with acute febrile illness with two
or more organ dysfunction were screened for the inclusion and
exclusion criterias.
Results: A total of 213 cases of acute febrile illness with one
or more organ dysfunction were screened. Of the screened
patients 75 patients were finally included in the study out of
which 46 (61.3%) patients were males and 29 (38.7%) patients
were females. Aetiology for acute febrile illness with MODS
could be established in 49 (65.3%) patients and it was obscure
in 26 (34.7%) patients despite repeated investigations. Dengue
infection (29.3%) was the commonest cause of febrile illness
with MODS followed by leptospirosis (22.7%). Majority of
these patients had haematological derangements (78.7%)
and liver function test abnormalities (68%). Out of these 75
cases, 54 (72%) patients recovered completely and 21 (28%)
patients died. Among males (N=46), 35 (76.1%) patients
recovered and 11 (23.9%) patients died where as among
females (N=29), 19 (65.5%) patients recovered and 10 (34.5%)
patients died. Mortality was proportionate with the number of
organ dysfunction, especially Central Nervous System (CNS)
involvement.
Conclusion: Incidence of febrile illness with MODS is more
prevalent in males but the outcome appears poorer among
females. The diagnosis remained obscure in a sizable proportion
of these patients. Prognosis was inversely dependent on the
number of organs involved especially with CNS manifestations.
| Reference Key |
muthaiah2016journalstudy
Use this key to autocite in the manuscript while using
SciMatic Manuscript Manager or Thesis Manager
|
|---|---|
| Authors | ;Bhanukumar Muthaiah;Thippeswamy Thippeswamy;Srinivas Kondareddy;Prathima Chikkegowda |
| Journal | JAMA network open |
| Year | 2016 |
| DOI |
10.7860/JCDR/2016/21376.8301
|
| URL | |
| Keywords |
Citations
No citations found. To add a citation, contact the admin at info@scimatic.org
Comments
No comments yet. Be the first to comment on this article.