frequency of p16ink4a and p14arf genes methylation and its impact on bladder cancer cases in north indian population
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ID: 169847
2010
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Abstract
Introduction: Amongst the genitourinary cancers, carcinoma of the urinary bladder is one of the leading causes of death in India. Hypermethylation of the CpG islands of gene promoter is one of the earliest and most frequent epigenetic alterations leading to cancer as well as in its development. Several studies have suggested that tumour suppressor genes play a key role in the development of cancer. Methylation in the CDKN2A has been associated with various malignant diseases, but information with respect to urinary bladder cancer is lacking in north Indian population.
| Reference Key |
hosseini2010diseasefrequency
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|---|---|
| Authors | ;Seyed Ali Hosseini;Ranbir Chander Sobti;Kianoosh Malekzadeh;Shrawan Kumar Singh;Kusum Joshi |
| Journal | international journal of psychology : journal international de psychologie |
| Year | 2010 |
| DOI |
10.3233/DMA-2010-0716
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