evaluation of antimicrobial activity of probiotic lactobacillus strains against growth and urease activity of proteus spp.

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2017
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Abstract

Background:    Nowadays, the use of probiotic bacteria for the prevention and treatment of urinary tract infections is growing. Lactobacillus, as probiotic bacterial genus, is well known for its benefits for the human health.

Methods:      The effects of partially purified antimicrobial compounds (bacteriocins and biosurfactants) of Lactobacillus strains was assessed and their capacity to in vitro inhibit growth and urease production of various strains of Proteus spp, was studied. Inhibition of the urease production of Proteus spp. at sub-MIC levels was screened using spectrophotometry method.  

Results:   Results revealed that semi-purified bacteriocins of L. acidophilus and L. plantarum showed a greater inhibitory activity on the bacterial urease, compared to biosurfactants of L. rhamnosus, L. casei and L. fermentum (P < 0.05).

Conclusion:    It can be concluded that bacteriocins may affect Proteus pathogenesis by inhibition of the bacterial urease activity and therefore eliminate the stone formation by these bacteria.
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goudarzi2017journalevaluation Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Leila Goudarzi;Rouha Kasra Kermanshahi;Zahra Moosavi-Nejad;Mohammad Mehdi Soltan Dalla
Journal journal of food and drug analysis
Year 2017
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