lamivudine for the treatment of membranous glomerulopathy secondary to chronic hepatitis b infection

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ID: 169351
2005
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Abstract
Membranous glomerulopathy is a well-recognized extrahepatic manifestation of chronic hepatitis B virus (HBV) infection. The authors report two cases of HBV-related nephrotic syndrome treated with lamivudine. A 46-year-old Chinese man had a hepatitis B e antigen seroconversion along with improvement in his nephrotic syndrome after lamivudine therapy. Two years after treatment was discontinued, a reactivation of HBV was successfully treated again with lamivudine. A 44-year-old Chinese woman, who was intolerant of interferon, was treated with lamivudine for 15 months without a virological response. However, two years after completing lamivudine, her nephrotic syndrome resolved. Implications for the treatment of HBV-related glomerulopathy and a review of the literature are presented.
Reference Key
gan2005canadianlamivudine Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;SI Gan;SM Devlin;NW Scott-Douglas;KW Burak
Journal indian journal of pharmacology
Year 2005
DOI
10.1155/2005/378587
URL
http://dx.doi.org/10.1155/2005/378587
Keywords
Gastroenterology diseases of the digestive system

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