expression of matrix metalloproteinase-9 in adenocarcinoma of prostate
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Abstract
Iimmunohistochemical study of cells proliferative activity by Ki-67 protein and localization of matrix metalloproteinase-9 (MMP-9) has been carried out at benign prostatic hyperplasia and adenocarcinoma of different gradations by the Gleason score. A significant decrease of the MMP-9 levels in the adenocarcinoma of different gradations have been found. A moderate positive correlation between the Gleason score and cell proliferation Ki-67 index (rs = 0.674) and a moderate negative correlation with the level of such score and expression of MMP-9 (rs = –0.660) were detected
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andruchin2014onkourologiexpression
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| Authors | ;M. I. Andruchin;S. A. Pulbere;A. V. Loktev;I. I. Babichenko |
| Journal | supportive care in cancer |
| Year | 2014 |
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