acute glomerulonephritis in children: a seven-year experience in a tertiary health center

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2012
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Abstract
Objectives: The aim of this study was to examine clinicaland laboratory characteristics of children with AGN in atertiary university hospital.Materials and methods: Hospital records of childrenwhich hospitalized with AGN diagnosis in Pediatric NephrologyUnit, between 2004 and 2011, were retrospectivelyreviewed. Patients were divided into threesubgroups as age <5 years, 5-10 years and >10 years.Characteristics at hospital admission including, bloodpressure, diuresis state, serum urea, creatinine and electrolytelevels, complement factors C3 and C4, completeblood count and urine analysis results were recorded.Data about primary infection, treatments, disease courseand outcome were recorded and analyzed.Results: Totally 220 children (157 male, 71.2%; 63 female,28.8%) were included. Probable etiological infectionswere tonsillopharyngitis in 133 (60.5%), pyodermain 12 (5.5%), other infections in 27 (12.2%) children. In48 (21.8) children with AGN, no primary infection weredetected. Edema was found in 81.4% of patients, hypertensionin 73.6%, and pulmonary stasis in 22.6%. Low C3levels were found in 89.1%, azotemia in 45.9%, hematuriain 95.4%, nephritic proteinuria in 80.5%, and leukocyturiain 37.6% of patients. Diuresis was enabled withinone week in 82%. Additional vasodilators were given to45 (20.5%) patients, and hemodialysis was performedto three. Except for frequency of low C3 (p=0.018) andanemia (p=0.006), no significant differences were foundin clinical and laboratory findings between age groups(p>0.05).Conclusions: No difference was found in clinical andlaboratory features of AGN based on age groups, excludinglow C3 and anemia frequency. J Clin Exp Invest 2012;3 (3): 357-362Key words: Acute glomerulonephritis, childhood, clinicalfindings, laboratory findings, age grops
Reference Key
gne2012journalacute Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Ali Güneş;Aydın Ece;Servet Yel;İlyas Yolbaş;Ünal Uluca;İlhan Tan;Velat Şen
Journal journal of solid state chemistry
Year 2012
DOI
DOI not found
URL
http://jceionline.org/upload/sayi/10/JCEI-00464.pdf
Keywords
childhood age gropsmedicine

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