massive fetomaternal hemorrhage caused by an intraplacental choriocarcinoma: a case report
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2010
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Abstract
Background. Intraplacental choriocarcinoma is a rare but highly malignant trophoblastic neoplasm. When found near term the risk of maternal metastasis is high because of the late diagnosis.
Case. We describe a case of an intraplacental choriocarcinoma diagnosed postpartum after a near-term delivery of a severely anemic infant. A fetomaternal hemorrhage resulted in a hemoglobin concentration in the infant of only 2,1 g/dL. Neither mother nor child showed signs of metastatic disease.
The macroscopic examination showed a hydropic placenta weighing more than 1 kilogram. Microscopy showed an intraplacental choriocarcinoma 3 cm in diameter. The tumor had infiltrated the maternal basal plate.
Conclusion. Fetomaternal bleeding is a rare form of presentation of choriocarcinoma but its presence should always warrant detailed examination of placenta, mother, and infant.
| Reference Key |
henningsen2010casemassive
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|---|---|
| Authors | ;Anna-Karina Aaris Henningsen;Lisa Leth Maroun;Hanne Havsteen;Jens Svare |
| Journal | Frontiers in pharmacology |
| Year | 2010 |
| DOI |
10.1155/2010/767218
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| URL | |
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