colchicine-related polyneuropathy and multiple organ failure

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ID: 159702
2013
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Abstract
Colchicine arrests microtubule assembly and inhibits many cellular functions. This drug is used to treat gout and and Familial Mediterranean Fever. Its gastrointestinal side effects are frequent but more severe adverse effects such as neuropathy and multi-organ failure associated with colchicine are rare. The blood levels of colchicine are dependent on the liver and kidneys. Thus renal or liver failure can result in colchicine toxication. We presented a case of colchicine toxicity, which resulted in multi-organ failure and polyneuropathy
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Authors ;Ersel Dağ;Yakup Türkel;Burcu Gökçe
Journal primates; journal of primatology
Year 2013
DOI
10.4274/Tnd.04557
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