click chemistry approach to a series of calcitriol analogues with heterocyclic side chains

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ID: 157620
2016
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Ranked #17 of 26 articles by views in value in health : the journal of the international society for pharmacoeconomics and outcomes research

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Abstract

We report a straightforward synthesis of a series of novel calcitriol analogues from vitamin D2with some modification of the procedures described by Calverley and Choudhry. This approach allows the large scale synthesis of a late-stage intermediate common to all the analogues of the series.This intermediate was successfully employed to synthesize a huge number of calcitriol analogues using a “click” chemistry approach. 

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gndara2016mediterraneanclick Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Zoila Gándara;Pedro-Lois Suárez;Alioune Fall;Massène Sène;Ousmane Diouf;Mohamed Gaye;Generosa Gómez;yagamare fall
Journal value in health : the journal of the international society for pharmacoeconomics and outcomes research
Year 2016
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