the effect of oral administration of fermented rice by monascus purpureus jmba on blood of hypercholesterolemia white mouse (rattus sp.)

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ID: 157022
2006
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Abstract
Fermented rice by Monascus purpureus, namely angkak, produces lovastatin. Lovastatin is believed and studied as anti-hypercholesterolemic agent. Somehow, its effects on blood parameters were less known. Therefore, a study on the effect of angkak on erythrocyte, leukocyte, thrombocyte, and haemoglobin level was conducted, involving 15 male Sprague Dawley strain white mice that were divided into 5 treatment groups. The result showed that oral administration of angkak beared lovastatin to the hipercholesterolemic mice could increase the number of trombocyte during the study. Increasing the number of thrombocyte was different depended on dosage of angkak. The optimum dosage was 0.1 g/day. Angkak could also increase haemoglobin concentration and the number of leucocyte, although that raise did not depend on dosage of angkak. Meanwhile, the number of erythrocyte was not affected by angkak.
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nurhidayat2006biodiversitasthe Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;NOVIK NURHIDAYAT;EVI TRIANA
Journal Journal of endourology
Year 2006
DOI
DOI not found
URL
http://biodiversitas.mipa.uns.ac.id/D/D0704/D070404.pdf
Keywords
hemoglobin lovastatin thrombocytebiology (general)

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