micro-imagerie par résonance magnétique nucléaire : application à la structure trabéculaire osseuse nuclear magnetic resonance micro-imagery applied to the trabecular structure in bone
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ID: 155434
2006
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Abstract
L'ostéoporose est une maladie caractérisée par une baisse de densité osseuse et une altération de la microarchitecture trabéculaire. Le but de ce travail est la validation d'une technique d'évaluation de l'architecture osseuse effectuée à partir de clichés radiographiques. Dans une première phase, nous avons mis en place un protocole expérimental permettant de reconstruire un modèle numérique 3D du tissu osseux à partir de la technique d'imagerie par résonance magnétique (IRM). Différents outils de caractérisation 3D, tant morphologiques que topologiques, ainsi qu'un outil de simulation numérique du processus radiographique ont été développés et appliqués sur ce modèle. Dans une deuxième phase, nous utiliserons ces outils afin de mettre en évidence des corrélations entre les caractéristiques 3D de la structure et celles de sa projection radiographique.
Osteoporosis is a disease that is characterized by loss of bone density and alteration of the trabecular microarchitecture. The aim of this work is to validate a technique for evaluating the bone architecture using X-ray pictures. In the first phase, we established a protocol for constructing a 3D numerical model of bone tissue using Magnetic Resonance Imaging (MRI). Tools capable of both morphological and topological 3D characterization as well as a tool for numerically simulating X-rays were developed and applied using this model. In the second phase, we used these tools to demonstrate the correlations between the 3D characteristics of the cell structure and its X-ray projection.
Osteoporosis is a disease that is characterized by loss of bone density and alteration of the trabecular microarchitecture. The aim of this work is to validate a technique for evaluating the bone architecture using X-ray pictures. In the first phase, we established a protocol for constructing a 3D numerical model of bone tissue using Magnetic Resonance Imaging (MRI). Tools capable of both morphological and topological 3D characterization as well as a tool for numerically simulating X-rays were developed and applied using this model. In the second phase, we used these tools to demonstrate the correlations between the 3D characteristics of the cell structure and its X-ray projection.
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| Authors | ;Pothuaud L.;Porion P.;Levitz P.;Lespessailles E.;Benhamou C. L. |
| Journal | addiction (abingdon, england) |
| Year | 2006 |
| DOI |
10.2516/ogst:1998044
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