regression of post-transplant kaposi′s sarcoma after replacing cyclosporine with mycophenolate mofetil

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ID: 154496
2001
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Abstract
Kaposi′s sarcoma (KS) has been recently linked with human herpes virus-8 (HHV-8) infection. Other risk factors include the use of cyclosporine and polyclonal anti-lymphocyte sera. Reduction of the immunosuppression, in particular cyclosporine, leads to regression or disappearance of the tumor in a significant number of patients. There are few publications about the response of the tumor to the newer immunosuppressive agent mycophenolate mofetil (MMF). We describe here a 52-year-old woman, who developed KS 22 months after living related transplantation. The sarcoma lesions disappeared after replacing cyclosporine and azathioprine by MMF, while the allograft function remained stable. This case suggests the importance of discontinuation of cyclosporine in the treatment of post-transplant KS. MMF, while maintaining allograft function in the absence of cyclosporine, apparently did not interfere with the regression of the tumor.
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magdi2001saudiregression Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Hussein Magdi;Mooij Jacob;Roujouleh Haysam
Journal 15th ibero-american conference on software engineering, cibse 2012
Year 2001
DOI
DOI not found
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http://www.sjkdt.org/article.asp?issn=1319-2442;year=2001;volume=12;issue=1;spage=42;epage=44;aulast=Hussein
Keywords
Medicine transplantation immunosuppression mycophenolate mofetil

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