micrornas: biological regulators in pathogen–host interactions

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ID: 154248
2020
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Abstract
An inflammatory response is essential for combating invading pathogens. Several effector components, as well as immune cell populations, are involved in mounting an immune response, thereby destroying pathogenic organisms such as bacteria, fungi, viruses, and parasites. In the past decade, microRNAs (miRNAs), a group of noncoding small RNAs, have emerged as functionally significant regulatory molecules with the significant capability of fine-tuning biological processes. The important role of miRNAs in inflammation and immune responses is highlighted by studies in which the regulation of miRNAs in the host was shown to be related to infectious diseases and associated with the eradication or susceptibility of the infection. Here, we review the biological aspects of microRNAs, focusing on their roles as regulators of gene expression during pathogen−host interactions and their implications in the immune response against Leishmania, Trypanosoma, Toxoplasma, and Plasmodium infectious diseases.
Reference Key
acua2020cellsmicrornas: Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Stephanie Maia Acuña;Lucile Maria Floeter-Winter;Sandra Marcia Muxel
Journal Frontiers in psychology
Year 2020
DOI
10.3390/cells9010113
URL
https://www.mdpi.com/2073-4409/9/1/113
Keywords
gene expression parasite micrornas pathogen host

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