clinical significance of 5αα-reductase and androgen receptor gene polymorphisms in prostate cancer

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ID: 153730
2014
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Abstract

The development of prostate cancer is inseparably linked with the effect of androgens on the fundamental prostatic intracellular processes,such as proliferation, apoptosis, which is realized through a number of second messengers. Major of them are the AR gene encoding androgenreceptors and the SRD5A2 gene encoding 5α-reductase enzyme. This paper deals with the study of the role of these genes in prostate cancer. 

 

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loran2014onkourologiclinical Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;O. B. Loran;I. V. Lukyanov;D. Yu. Tuzov;A. N. Tyulpakov
Journal supportive care in cancer
Year 2014
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