enhanced international prognostic index in japanese patients with diffuse large b-cell lymphoma

Clicks: 317
ID: 151338
2016
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Abstract
To evaluate the National Comprehensive Cancer Network (NCCN) International Prognostic Index (IPI), we analyzed 284 patients treated with the combination of rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) in our institution in Japan. Their 5-year overall survival (OS) by risk level was 80.7%, 74.8%, 55.4% and 67.5% (P=0.005); and their 5-year progression-free survival (PFS) was 76.8%, 78.6%, 63.7% and 58.3% (P=0.0722). The NCCN-IPI is a simple scale that uses conventional clinical factors, but did not reflect survival in our cohort. The NCCN-IPI may require further evaluation for different regions and ethnicities before adopting it for routine clinical use.
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nakaya2016leukemiaenhanced Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Aya Nakaya;Shinya Fujita;Atsushi Satake;Takahisa Nakanishi;Yoshiko Azuma;Yukie Tsubokura;Masaaki Hotta;Hideaki Yoshimura;Kazuyoshi Ishii;Tomoki Ito;Shosaku Nomura
Journal urology annals
Year 2016
DOI
10.1016/j.lrr.2016.06.003
URL
http://www.sciencedirect.com/science/article/pii/S2213048916300140
Keywords
rituximab Oncology including cancer and carcinogens tumors albuminneoplasms

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