male androgenetic alopecia : response to finasteride

Clicks: 169
ID: 151240
2004
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Abstract
Androgenetic alopecia (AGA) is one of the most common causes of hair loss in genetically predisposed men and women. We studied the therapeutic efficacy and safety of oral finasteride in male patients with AGA. A total of 40 male AGA patients, 18-35 years of age, wad enrolled in the study for a period of 9 months. Oral finasteride, 1mg/day, was started and the drug efficacy was assessed on the basis of pre- and post-treatment clinical photographs, trichogram, hair pull test and self assessment of hair re-growth by the investigators. Routine hematological and bio-chemical investigations and a questionnaire related to sexual disturbances were carried out to assess the safety profile of the drug at each follow-up visit every three months. Improvement in hair growth was observed by comparing the paired pre- and post-treatment global photographs (p<0.05), decreased hair shedding by the patients’ self assessment (p<0.05), hair pull test evaluation (p<0.001) and increase in anagen-telogen hair ratio (p<0.001) with the trichogram, as early as 3 months of finasteride therapy with maximum benefit in the mid-area followed by vertex and frontal areas. No significant side effect related to the drug was observed. It is concluded that oral finasteride is a relatively safe, well tolerated and efficacious drug for AGA in Males.
Reference Key
suruchi2004indianmale Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Thakkar Suruchi;Reddy B. S. N
Journal heterocycles
Year 2004
DOI
DOI not found
URL
http://www.e-ijd.org/article.asp?issn=0019-5154;year=2004;volume=49;issue=3;spage=123;epage=127;aulast=Thakkar;type=0
Keywords
dermatology

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