biomedical properties and potentiality of lippia microphylla cham. and its essential oils
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ID: 149668
2015
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Abstract
Lippia microphylla Cham. (Verbanaceae) is an endemic underexploited Brazilian vegetal. This work reviewed the biological potentialities of Lippia microphylla, emphasizing the properties of essential oils (EOs) and analyzed scientific indicators about genus Lippia and L. microphylla. Databases from 1948 to the present were searched and a software (Vantage Point 7.1) associated with Derwent Innovation Index was used to identify the indicators of the genus Lippia, and biological activities and compounds in the L. macrophylla species. Ethnopharmacological records report use of L. microphylla leaves to treat gastrointestinal disorders, influenza, bronchitis, cough, nasal congestion and sinusitis during vaporization, whose aromatic volatile oils are rich in monoterpenes, especially cineole, terpineol and thymol. Other EOs have larvicidal activity on Aedes aegypti larvae, and antifungal, antibacterial and cytotoxic and antitumor action on human and murine cancer cells. Brazil is the country with more articles about Lippia species, but it deposited only 9 patents since 1993. Most of the publications about L. microphylla are concentrated in food and chemical sciences. This bioprospection helps to choice areas of interest for capital investment and to give support for Brazilian Institutions to establish cooperation and improve technological impact at the point of view of creation and innovation. [J Intercult Ethnopharmacol 2015; 4(3.000): 256-263]
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otilde;es2015journalbiomedical
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| Authors | ;Evelyne Rolim Braun Sim and otilde;es;Evelyne Alves Santos;Maria Carolina de Abreu;Jurandy do Nascimento Silva;N and aacute;rcia Mariana Fonseca Nunes;Marc and iacute;lia Pinheiro da Costa;Ot and iacute;lia Deusd and ecirc;nia Loiola Pessoa;Cl and aacute;udia Pessoa;Paulo Michel Pinheiro Ferreira |
| Journal | jurnal farmasi galenika (galenika journal of pharmacy) |
| Year | 2015 |
| DOI |
10.5455/jice.20150610104841
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| URL | |
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