Generation of CSi001-A, a transgene-free, induced pluripotent stem cell line derived from a Parkinson Disease (PD) patient.
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ID: 14768
2018
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Abstract
Peripheral blood mononuclear cells (PBMC) were collected from a 70-year old Parkinson Disease patient. The PBMCs were reprogrammed with the human OKSM transcription factors using the non-integrating episomal vector system. The transgene-free iPSC showed pluripotency verified by immunocytochemistry for pluripotency markers and differentiated directly toward the 3 germ layers in vitro. Furthermore, the iPSC line showed normal karyotype.
| Reference Key |
zhao2018generationstem
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|---|---|
| Authors | Zhao, Zongbo;Ji, Sunping;Shi, Zhige;Liu, Hui; |
| Journal | Stem cell research |
| Year | 2018 |
| DOI |
S1873-5061(18)30241-1
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| URL | |
| Keywords | Keywords not found |
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