Generation of two human isogenic iPSC lines from fetal dermal fibroblasts.

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ID: 14767
2018
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Abstract
Two isogenic hiPSC lines, ZIPi013-B and ZIPi013-E, were generated by reprogramming fetal dermal fibroblasts with episomal vectors. Previously, the same fetal fibroblasts were reprogrammed multiple times in a study comparing other reprogramming methods. As a consequence, the genomes have been sequenced multiple times. Both new cell lines offer the opportunity to study basic stem cell biology and model human disease. They can be applied as reference cell lines for creating isogenic clones bearing disease mutations on a well-characterized genomic background, as both cell lines have demonstrated excellent differentiation capacity in multiple labs. Resource table.
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tandon2018generationstem Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Tandon, Rashmi;Brändl, Björn;Baryshnikova, Natalya;Landshammer, Alexandro;Steenpaß, Laura;Keminer, Oliver;Pless, Ole;Müller, Franz-Josef;
Journal Stem cell research
Year 2018
DOI
S1873-5061(18)30247-2
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