synthesis of substituted thieno[2,3-d]pyrimidin-4-ones and their testing for evaluation of cytotoxic activity on mammalian cell models
Clicks: 220
ID: 147594
2013
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This
article has not been analysed, so there is no overall score —
reader engagement is measured and shown alongside.
Reader Engagement
Popular Article
30.0
/100
220 views
29 readers
AI Quality Assessment
Not analyzed
Readership in this journal
PopularRanked #37 of 215 articles by views in british journal of psychology (london, england : 1953)
Most read
Least read
Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 215 in total.
Mint this article as an NFT
Not yet mintedCreate a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.
5
SUSD
one-off · no wallet required
Abstract
From 2-amino-3-ethoxycarbonyl-4,5-dimethyl-, -polymethylenethiophenes (1-4) were synthesized 2,3-disubstituted thieno[2,3-d]dihydropyrrolo-, tetrahydropyrido-, and tetrahydroazepino[1,2-a]pyrimidin-4-ones (5-16) for pharmacological investigations. The 12 compounds (5-16) were individually evaluated for their antiproliferative activities on mammalian cancer cell models. All tested compounds showed weak affection on human cervix adenocarcinoma cells (HeLa) whereas some of the tested compounds exhibited more consistent inhibition of cell growth on murine myeloma cells (P3X). In both cases some compounds enhanced cell proliferation.
| Reference Key |
bozorov2013journalsynthesis
Use this key to autocite in the manuscript while using
SciMatic Manuscript Manager or Thesis Manager
|
|---|---|
| Authors | ;Kh. A. Bozorov;N. Z. Mamadalieva;B. Zh. Elmuradov;D. Triggiani;D. Egamberdieva;A. Tiezzi;H. A. Aisa;Kh. M. Shakhidoyatov |
| Journal | british journal of psychology (london, england : 1953) |
| Year | 2013 |
| DOI |
10.1155/2013/976715
|
| URL | |
| Keywords |
Citations
No citations found. To add a citation, contact the admin at info@scimatic.org
Comments
No comments yet. Be the first to comment on this article.