crl ubiquitin ligases and dna damage response
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ID: 145998
2012
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Abstract
Cullin/RING ubiquitin ligases (CRL) comprise the largest subfamily of ubiquitin ligases and are involved in various biological processes. One of the main functions of CRLs is to regulate DNA damage response, a fundamental signaling cascade to maintain genome integrity. In this review, we will discuss the regulation of CRL ubiquitin ligases and their roles in control of DNA damage response.
| Reference Key |
ejin2012frontierscrl
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|---|---|
| Authors | ;Jianping eJin;Ju-Mei eLi |
| Journal | international journal of heat and technology |
| Year | 2012 |
| DOI |
10.3389/fonc.2012.00029
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| URL | |
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