the laboratorial diagnosis of dengue: applications and implications

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ID: 145599
2009
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Abstract
The diagnosis of infection by the dengue virus relies, in most cases, on the clinical judgment of the patient, since only a few major centers have clinical laboratories that offer diagnostic tests to confirm the clinical impressions of an infection. At present, routine laboratory diagnosis is done by different kinds of testing. Among them are the methods of serological research, virus isolation, detection of viral antigens, and detection of viral genomes. The continued development of diagnostic tests, which are cheap, sensitive, specific, easy to perform, and capable of giving early diagnosis of the dengue virus infection is still a need. There are also other obstacles that are not specifically related to the technological development of diagnostic methods. For instance, infrastructure of the laboratories, the training of personnel, and the capacity of research of these laboratories are still limited in many parts of Brazil and the world, where dengue is endemic. Clinical laboratories, especially the ones that serve regions with a high incidence of dengue, should be aware of all the diagnostic methods available for routine these days, and choose the one that best suit their working conditions and populations served, in order to save lives.
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dutra2009journalthe Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Nina Rocha Dutra;Marilia Barbosa de Paula;Michelle Dias de Oliveira;Leandro Licursi de Oliveira;Sergio Oliveira de Paula
Journal Applied Physics Letters
Year 2009
DOI
10.4103/0974-777X.52980
URL
http://www.jgid.org/article.asp?issn=0974-777X;year=2009;volume=1;issue=1;spage=38;epage=44;aulast=Dutra
Keywords
dengue clinical laboratory diagnosis infectious and parasitic diseases

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