recent advances in chemotherapy for head and neck cancers

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ID: 144464
2012
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Abstract
Systemic chemotherapy is increasingly being used with radiotherapy for the radical treatment of advanced head and neck cancers. Chemotherapy offers modest benefits in the metastatic setting. Platinum containing agents are the most active drugs and form the mainstay of most chemotherapy schedules. In recent years taxanes have shown activity in head and neck cancers and are being -incorporated into neo-adjuvant and concomitant chemotherapy regimens. Targeted agents and epidermal growth factor receptor (EGFR) inhibitors, like cetuximab, in particular, have shown benefit in the metastatic and the concomitant setting. EGFR inhibitors and other targeted agents form the thrust of pre-clinical and clinical research into the systemic treatment of head and neck cancers.
Reference Key
sambargi2012journalrecent Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Uma C Sambargi;D R Mahesh;Anuradha Pai;Prathima Maligi;B K Ramanarayan;C J Sanjay
Journal BMC medical informatics and decision making
Year 2012
DOI
10.4103/0975-8844.99880
URL
http://www.jofs.in/article.asp?issn=0975-8844;year=2012;volume=4;issue=1;spage=15;epage=19;aulast=Sambargi
Keywords
head and neck cancers chemotherapy

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