synthetic studies towards d-modified paclitaxel analogues
Clicks: 142
ID: 144089
2012
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This
article has not been analysed, so there is no overall score —
reader engagement is measured and shown alongside.
Reader Engagement
Popular Article
30.0
/100
142 views
19 readers
AI Quality Assessment
Not analyzed
Readership in this journal
PopularRanked #123 of 151 articles by views in meditsinskaia radiologiia
Most read
Least read
Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 151 in total.
Mint this article as an NFT
Not yet mintedCreate a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.
5
SUSD
one-off · no wallet required
Abstract
A synthetic sequence has been developed for the preparation of 9,10-O-diacetyl-4-desmethylene-4β-(3-butenyl)-4α-hydroxy-5-O-mesyltaxicin I-1,2-carbonate 3, an intermediate in the attempted synthesis of cyclobutane paclitaxel analogue. A series of reactions of 3 has been investigated, including the protection of sterically hindered C-4α hydroxy group and oxidative cleavage of the terminal double bond. Cyclization of 13 to the cyclobutane-containing intermediate failed due to unexpected instability of the DMS protecting group under basic conditions. [Acknowledgments. Financial support of the Ministry of Education and Science of the Republic of Serbia is acknowledged (Project No. 172027)]
Abstract Quality Issue:
This abstract appears to be incomplete or contains metadata (92 words).
Try re-searching for a better abstract.
| Reference Key |
radomir2012journalsynthetic
Use this key to autocite in the manuscript while using
SciMatic Manuscript Manager or Thesis Manager
|
|---|---|
| Authors | ;Matović Radomir;Saičić Radomir N.;Ferjančić Zorana |
| Journal | meditsinskaia radiologiia |
| Year | 2012 |
| DOI |
10.2298/JSC120626094F
|
| URL | |
| Keywords |
Citations
No citations found. To add a citation, contact the admin at info@scimatic.org
Comments
No comments yet. Be the first to comment on this article.