analgesia e sedação da s(+) cetamina e da s(+) cetamina-morfina, associadas à ropivacaína, por via peridural, no pós-operatório de intervenção cirúrgica de abdômen superior analgesia y sedación de la s(+) cetamina y de la s(+) cetamina-morfina, asociadas a la ropivacaína, por vía peridural, en el postoperatorio de intervención quirúrgica de abdomen superior epidural s(+) ketamine and s(+) ketamine-morphine associated with ropivacaine in the postoperative analgesia and sedation of upper abdominal surgery
Clicks: 375
ID: 143909
2007
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This
article has not been analysed, so there is no overall score —
reader engagement is measured and shown alongside.
Reader Engagement
Popular Article
30.1
/100
375 views
77 readers
AI Quality Assessment
Not analyzed
Readership in this journal
PopularRanked #35 of 139 articles by views in methods in molecular biology (clifton, nj)
Most read
Least read
Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 139 in total.
Mint this article as an NFT
Not yet mintedCreate a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.
5
SUSD
one-off · no wallet required
Abstract
JUSTIFICATIVA E OBJETIVOS: A combinação de fármacos, atuando por diferentes mecanismos de ação no corno dorsal da medula espinhal, acarreta diminuição da dor pós-operatória, com menor incidência de efeitos colaterais. O objetivo foi avaliar a analgesia e a sedação pós-operatórias causadas pela S(+) cetamina e S(+) cetamina-morfina associadas à ropivacaína, por via peridural, em colecistectomia por via subcostal. MÉTODO: Participaram do estudo 70 pacientes, de ambos os sexos, estado físico ASA I e II. Foram administradas por via peridural: ropivacaína a 0,75% associada ao cloreto de sódio a 0,9% no Grupo-controle (GC); ropivacaína a 0,75% associada à S(+) cetamina (0,5 mg.kg-1) no Grupo Cetamina (GK); ropivacaína a 0,75% associada à S(+) cetamina (0,5 mg.kg-1) e à morfina (2 mg) no Grupo Cetamina-Morfina2 (GKM2); ropivacaína a 0,75% associada à S(+) cetamina (0,5 mg.kg-1) e à morfina (3 mg) no Grupo Cetamina-Morfina3 (GKM3). A analgesia e a sedação foram observadas às duas, seis e 24 horas após o término do ato operatório. RESULTADOS: A sedação foi observada até duas horas após o término do ato operatório nos grupos GK, GKM2 e GKM3. A analgesia foi efetiva no GC até duas horas de pós-operatório, no GK nas duas e seis horas; nos GKM2 e GKM3, nas 2h, 6h e 24h. CONCLUSÕES: A S(+) cetamina e as associações S(+) cetamina-morfina promoveram sedação até duas horas após o término de ato operatório. A S(+) cetamina promoveu analgesia especialmente no momento de observação de duas horas e as associações S(+) cetamina-morfina promoveram analgesia sobretudo nos momentos de observação de 2h e 6h após o término do ato operatório.
JUSTIFICATIVA Y OBJETIVOS: La combinación de fármacos, actuando por diferentes mecanismos de acción en el cuerno dorsal de la médula espinal, acarrea una disminución del dolor postoperatorio, con una menor incidencia de los efectos colaterales. El objetivo fue el de evaluar la analgesia y la sedación postoperatorias causadas por la S(+) cetamina y S(+) cetamina-morfina asociadas a la ropivacaína, por vía peridural, en colecistectomía por vía subcostal. MÉTODO: Participaron del estudio 70 pacientes, de ambos sexos, estado físico ASA I y II. Se administraron por vía peridural: ropivacaína a 0,75% asociada al cloruro de sodio a 0,9% en el Grupo Control (GC); ropivacaína a 0,75% asociada a la S(+) cetamina (0,5 mg.kg-1) en el Grupo Cetamina (GK); ropivacaína a 0,75% asociada à S(+) cetamina (0,5 mg.kg-1) y a la morfina (2 mg) en el Grupo Cetamina-Morfina2 (GKM2); ropivacaína a 0,75% asociada a la S(+) cetamina (0,5 mg.kg-1) y a la morfina (3 mg) en el Grupo Cetamina-Morfina3 (GKM3). La analgesia y la sedación fueron observadas a las 2h, 6h y 24h después del término de la operación. RESULTADOS: La sedación fue observada en 2h después de la operación en los grupos GK, GKM2 y GKM3. La analgesia quedó efectiva en el GC en 2h después del postoperatorio, en el GK en la 2h y 6h; en los GKM2 y GKM3 en las 2h, 6h y 24h. CONCLUSIONES: La S(+) cetamina y las asociaciones S(+) cetamina-morfina promovieron sedación hasta 2 horas después del término de la operación. La S(+) cetamina promovió analgesia especialmente 2 en horas y las asociaciones S(+) cetamina-morfina promovieron analgesia principalmente en los momentos de observación de 2h y 6h después del término de la operación.
BACKGROUND AND OBJECTIVES: The association of drugs with different mechanisms of action in the dorsal horn of the spinal cord decreases postoperative pain, with a reduction in the incidence of side effects. The aim of this study was to evaluate postoperative analgesia and sedation by epidural S(+) ketamine and S(+) ketamine-morphine associated with ropivacaine in subcostal cholecystectomy. METHODS: Seventy patients of both genders, physical status ASA I and II, participated in this study. The following drugs were administered epidurally: 0.75% ropivacaine associated with 0.9% sodium chloride in the Control Group (CG); 0.75% ropivacaine associated with S(+) ketamine (0.5 mg.kg-1) in the Ketamine Group (KG); 0.75% ropivacaine associated with S(+) ketamine (0.5 mg.kg-1) and morphine (2 mg) in the Ketamine-Morphine Group2 (KMG2); 0.75% ropivacaine associated with S(+) ketamine (0.5 mg.kg-1) and morphine (3 mg) in the Ketamine-Morphine Group3 (KMG3). Analgesia and sedation were evaluated 2h, 6h, and 24h after the end of the surgery. RESULTS: Sedation was observed up to 2 hours after the end of the procedure in KG, KMG2, and KMG3. Analgesia was effective in CG up to 2 hours after the surgery, at 2h and 6h in KG, and at 2h, 6h, and 24h, in KMG2 and KMG3. CONCLUSIONS: S(+) ketamine and the associations S(+) ketamine-morphine promoted sedation up to 2h after the end of the surgical procedure. S(+) ketamine promoted analgesia especially at the moment of the 2h observation, and the associations of S(+) ketamine-morphine promoted analgesia especially at 2h and 6h after the surgery.
JUSTIFICATIVA Y OBJETIVOS: La combinación de fármacos, actuando por diferentes mecanismos de acción en el cuerno dorsal de la médula espinal, acarrea una disminución del dolor postoperatorio, con una menor incidencia de los efectos colaterales. El objetivo fue el de evaluar la analgesia y la sedación postoperatorias causadas por la S(+) cetamina y S(+) cetamina-morfina asociadas a la ropivacaína, por vía peridural, en colecistectomía por vía subcostal. MÉTODO: Participaron del estudio 70 pacientes, de ambos sexos, estado físico ASA I y II. Se administraron por vía peridural: ropivacaína a 0,75% asociada al cloruro de sodio a 0,9% en el Grupo Control (GC); ropivacaína a 0,75% asociada a la S(+) cetamina (0,5 mg.kg-1) en el Grupo Cetamina (GK); ropivacaína a 0,75% asociada à S(+) cetamina (0,5 mg.kg-1) y a la morfina (2 mg) en el Grupo Cetamina-Morfina2 (GKM2); ropivacaína a 0,75% asociada a la S(+) cetamina (0,5 mg.kg-1) y a la morfina (3 mg) en el Grupo Cetamina-Morfina3 (GKM3). La analgesia y la sedación fueron observadas a las 2h, 6h y 24h después del término de la operación. RESULTADOS: La sedación fue observada en 2h después de la operación en los grupos GK, GKM2 y GKM3. La analgesia quedó efectiva en el GC en 2h después del postoperatorio, en el GK en la 2h y 6h; en los GKM2 y GKM3 en las 2h, 6h y 24h. CONCLUSIONES: La S(+) cetamina y las asociaciones S(+) cetamina-morfina promovieron sedación hasta 2 horas después del término de la operación. La S(+) cetamina promovió analgesia especialmente 2 en horas y las asociaciones S(+) cetamina-morfina promovieron analgesia principalmente en los momentos de observación de 2h y 6h después del término de la operación.
BACKGROUND AND OBJECTIVES: The association of drugs with different mechanisms of action in the dorsal horn of the spinal cord decreases postoperative pain, with a reduction in the incidence of side effects. The aim of this study was to evaluate postoperative analgesia and sedation by epidural S(+) ketamine and S(+) ketamine-morphine associated with ropivacaine in subcostal cholecystectomy. METHODS: Seventy patients of both genders, physical status ASA I and II, participated in this study. The following drugs were administered epidurally: 0.75% ropivacaine associated with 0.9% sodium chloride in the Control Group (CG); 0.75% ropivacaine associated with S(+) ketamine (0.5 mg.kg-1) in the Ketamine Group (KG); 0.75% ropivacaine associated with S(+) ketamine (0.5 mg.kg-1) and morphine (2 mg) in the Ketamine-Morphine Group2 (KMG2); 0.75% ropivacaine associated with S(+) ketamine (0.5 mg.kg-1) and morphine (3 mg) in the Ketamine-Morphine Group3 (KMG3). Analgesia and sedation were evaluated 2h, 6h, and 24h after the end of the surgery. RESULTS: Sedation was observed up to 2 hours after the end of the procedure in KG, KMG2, and KMG3. Analgesia was effective in CG up to 2 hours after the surgery, at 2h and 6h in KG, and at 2h, 6h, and 24h, in KMG2 and KMG3. CONCLUSIONS: S(+) ketamine and the associations S(+) ketamine-morphine promoted sedation up to 2h after the end of the surgical procedure. S(+) ketamine promoted analgesia especially at the moment of the 2h observation, and the associations of S(+) ketamine-morphine promoted analgesia especially at 2h and 6h after the surgery.
| Reference Key |
schnaider2007revistaanalgesia
Use this key to autocite in the manuscript while using
SciMatic Manuscript Manager or Thesis Manager
|
|---|---|
| Authors | ;Taylor Brandão Schnaider;Antônio Mauro Vieira;Antônio Carlos Aguiar Brandão;Aretusa Chediak Roquim |
| Journal | methods in molecular biology (clifton, nj) |
| Year | 2007 |
| DOI |
10.1590/S0034-70942007000100002
|
| URL | |
| Keywords |
Citations
No citations found. To add a citation, contact the admin at info@scimatic.org
ZincirX productsfrom the team behind Journament
-
PatentYazar
Patent drafts for the EPO, USPTO and TürkPatent
From inventor notes to a DOCX draft: description, claims, abstract. The machine drafts, the attorney signs.
See how it works (opens in a new tab) -
Projenator
Have a project idea? Score and plan it with AI
AI scores your idea in five dimensions and builds a phased plan. Your first project is free, no card needed.
Start your first project (opens in a new tab)
Cookies
We use strictly necessary cookies to run the site and keep you signed in. With your permission we would also use Google Analytics to see how the site is used, and Google AdSense to show ads on journal and article pages. Both stay off unless you accept, and you can change your mind at any time. How we use cookies · KVKK notice (Türkiye)
Cookie settings
Your session, form security (XSRF) and this choice; if you came through a member's referral link, its code for 30 days (referral_token). Journament's own cookies only.
Google Analytics 4 (Google LLC, USA): measures which pages are visited; the _ga and _ga_* cookies are kept for up to 2 years.
Google AdSense (Google LLC, USA): shows, measures and may personalise ads on journal, article and home pages; the __gads, __gpi and __eoi cookies are kept for up to 13 months.
Comments
No comments yet. Be the first to comment on this article.