hemólise na circulação extracorpórea: correlação com tempo e procedimentos realizados hemolysis in extracorporeal circulation: relationship between time and procedures

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ID: 142156
2012
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Abstract
INTRODUÇÃO: A circulação extracorpórea (CEC) é indispensável para a maioria das operações cardíacas, mas causa danos significantes ao sangue, dentre eles a hemólise. OBJETIVO: Quantificar as taxas de hemólise em diferentes tempos nas operações para revascularização do miocárdio com uso de CEC. MÉTODOS: Foram medidas as taxas de hemólise de 22 pacientes em 6 tempos distintos durante a revascularização do miocárdio com uso de CEC: T0 - antes do início da CEC, T1 - 5 minutos após o início da CEC, T2 - com 30 minutos de CEC, T3 - imediatamente antes do despinçamento da aorta, T4 - imediatamente antes da passagem do volume residual para o paciente e T5 - 5 minutos após o término da passagem do volume residual para o paciente. Foram calculadas as taxas de hemólise entre os intervalos de tempo: T0-T1; T1-T2; T2-T3; T3-T4 e T4-T5. RESULTADOS: Os primeiros 5 minutos após a CEC demonstraram maior taxa de hemólise (P = 0,0003) em comparação às outras taxas calculadas, representando 29% da hemólise total até T4 (imediatamente antes da passagem do volume residual para o paciente). CONCLUSÃO: Não foram observadas variações significantes nas taxas de hemólise durante a aspiração na raiz da aorta (P > 0,38) nem com o procedimento utilizado para a passagem do volume residual de sangue no circuito para os pacientes.
INTRODUCTION: Extracorporeal circulation (EC) is very important in cardiac surgery but causes significant damage to the blood, including hemolysis. OBJECTIVE: To quantify the rate of hemolysis at different times during EC in elective coronary artery bypass grafting. METHODS: We measured rates of hemolysis of 22 patients at 6 different times during myocardial revascularization during EC: T0 - before the start of EC, T1 - five minutes after of the EC initiation, T2 - 30 minutes of EC, T3 - immediately before the aortic unclamping, T4 - immediately before passage of the residual volume to the patient and T5 - five minutes after the passage of the residual volume to the patient. Rates of hemolysis were calculated between the intervals of time: T0-T1; T1-T2; T2-T3; T3-T4 and T4-T5. RESULTS: The first 5 minutes after the EC showed the highest rate of hemolysis (P = 0.0003) compared to the others calculated rates, representing 29% of the total haemolysis until T4 (Immediately before passage of the residual volume to the patient). CONCLUSION: There were no significant changes in the rate of hemolysis during the suction in the aortic root (P> 0.38), nor with the procedure used for the passage of the residual volume of blood in the circuit to the patient.
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Authors ;Francisco Ubaldo Vieira Junior;Nilson Antunes;Reinaldo Wilson Vieira;Lúcia Madalena Paulo Álvares;Eduardo Tavares Costa
Journal 2017 international conference on information technology systems and innovation, icitsi 2017 - proceedings
Year 2012
DOI
DOI not found
URL
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382012000400011
Keywords
hemolysis

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