juvenile x-linked retinoschisis responsive to intravitreal corticosteroids

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ID: 142145
2017
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Abstract
Purpose: To report the case of an adult male with X-linked retinoschisis (XLRS) who presented with cystoid macular edema (CME) that responded consistently to treatment with intravitreal steroids. Observations: A 39 year old male with unilateral presentation of CME after repair of a retinal detachment secondary to XLRS responded initially to an injection of intravitreal triamcinolone acetonide (IVTA). Central subfield thickness on OCT was reduced. Three months later, the CME recurred and he was unresponsive to topical treatment so repeat IVTA was given, and the CME once again was reduced dramatically. After the next recurrence, intravitreal dexamethasone implant treatment was initiated and successful at treating recurrences in 3 month intervals for 5 additional injections. Finally, an intravitreal fluocinolone acetonide implant was surgically placed with control of CME. Conclusions and importance: Corticosteroids have never been reported to be effective in CME related to XLRS. Here, we document a case of a man who successfully had decrease of intraretinal fluid and schisis with treatment of intravitreal corticosteroids as demonstrated by spectral domain optical coherence tomography.
Reference Key
ansari2017americanjuvenile Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Waseem H. Ansari;Andrew W. Browne;Rishi P. Singh
Journal contemporary clinical trials communications
Year 2017
DOI
10.1016/j.ajoc.2016.12.002
URL
http://www.sciencedirect.com/science/article/pii/S2451993616301256
Keywords
corticosteroids

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