Brd4 binds to active enhancers to control cell identity gene induction in adipogenesis and myogenesis

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ID: 14162
2017
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Abstract
Despite being an important cancer drug target, the role of epigenetic reader Brd4 in cell differentiation and development remains unclear. Here, the authors provide evidence that Brd4 plays an important role in adipogenesis and myogenesis by binding to active enhancers to regulate gene expression.
Reference Key
lee2017brd4nature Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Lee, Ji-Eun;Park, Young-Kwon;Park, Sarah;Jang, Younghoon;Waring, Nicholas;Dey, Anup;Ozato, Keiko;Lai, Binbin;Peng, Weiqun;Ge, Kai;
Journal Nature communications
Year 2017
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DOI not found
URL
http://link.springer.com/article/10.1038/s41467-017-02403-5
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