in vivo mucoadhesive strength appraisal of gum manilkara zapota

Clicks: 132
ID: 140453
2015
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Abstract
The mucilage (MMZ) extracted from the seeds of Manilkara zapota(Linn.) P. Royen syn. using maceration techniques was evaluated for mucoadhesive strength by various in vitro and in vivo methods. The result showed that mucoadhesive strength of seeds mucilage have comparable property toward natural and synthetic polymers such as Guar Gum and hydroxyl propyl methyl cellulose (HPMC E5LV) under the experimental conditions used in this study. Briefly, it could be concluded that the seed mucilage of Manilkara zapota can be used as a pharmaceutical excipient in oral mucoadhesive drug delivery systems. Further, it may be appropriate to study the changes in these properties after chemical modifications.
Reference Key
sudarshan2015brazilianin Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Singh Sudarshan;Bothara Sunil B
Journal electronic engineering times
Year 2015
DOI
10.1590/S1984-82502015000300021
URL
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000300689&lng=en&tlng=en
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