utilidade do ultrassom intracardíaco no isolamento de veias pulmonares usando cateter-balão a laser utilidad del ultrasonido intracardíaco en el aislamiento de venas pulmonares usando catéter-balón láser utility of intracardiac ultrasound imaging to guide pulmonary vein ablation using laser balloon catheter
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Abstract
FUNDAMENTO: Se usó el aislamiento de las venas pulmonares (AVP) como endpoint para la ablación de la fibrilación atrial (FA) con catéter-balón. OBJETIVO: Determinar la utilidad del ultrasonido intracardíaco (USIC) para guiar el AVP, usando catéter-balón láser. MÉTODOS: Se ablacionaron 59 VP en 27 perros. Se usaron imágenes de Doppler para identificar los derrames del flujo sanguíneo entre la VP y el balón. Tras cada liberación de energía, se reposicionó el catéter de mapeamiento circular para verificar si se obtuvo el aislamiento. Se correlaccionó, entonces, la posición del derrame con la posición del gap en el estudio patológico. Se realizó el análisis de regresión logística multivariada. RESULTADOS: Se sometieron 59 VP a la ablación. El tiempo promedio de energía liberada fue de 279±177 seg., el diámetro promedio del balón era de 23±3 mm, y la largura promedio del balón era 25±4 mm. Se obtuvo el aislamiento completo en 38/59 (64%), y fue significantemente más común sin derrame: [30/38 (79%) versus 8/23 (35%), p<0,001]. Eso fue independiente del tiempo de aplicación (302±223 seg. vs. 266±148 sec., p=ns), potencia (3,5 W/cm, 4,5 W/cm, y 5,5 W/cm), diámetro del balón (24± 3 mm vs. 22± 3 mm, p= ns) y largura (27±4 mm vs. 24±4 mm, p=ns). El valor predictivo positivo para la previsión del aislamiento completo fue del 65% y el valor predictivo negativo fue del 83%. CONCLUSIÓN: Un derrame identificable entre la VP y el dispositivo de ablación por catéter-balón observado en el USIC es predictor de menor tasa del aislamiento de la VP más baja. El USIC puede ser útil para detectar derrames a fin de evitar el uso ineficaz de la aplicación de la energía durante la ablación circunferencial de la VP. Ello también puede ser útil cuando se utilizan otras energías.
BACKGROUND: Pulmonary vein isolation (PVI) with balloon catheter has been used as the endpoint for AF ablation. OBJECTIVE: To determine the usefulness of intracardiac ultrasound (ICUS) to guide PVI using laser balloon catheter. METHODS: 59 PVs were ablated in 27 dogs. Doppler imaging was used to identify blood flow leaks between PV and balloon. After each energy delivery, the circular mapping catheter was repositioned to check if isolation had been achieved. The leak position was then correlated with the gap position at the pathological study. Multivariate logistic regression analysis was undertaken. RESULTS: 59 PV were ablated. Mean burn time was 279±177 sec, mean balloon diameter was 23±3 mm, and mean balloon length was 25±4 mm. Complete isolation was achieved in 38/59 (64%) cases, and it was significantly more common when there was no leak: [30/38 (79%) versus 8/23 (35%), p<0.001]. This occurred regardless of time of laser application (302±223 sec. vs. 266±148 sec., p=ns), laser power (3.5 W/cm, 4.5 W/cm, and 5.5 W/cm), balloon diameter (24± 3 mm vs. 22± 3 mm, p=ns) and length (27±4 mm vs. 24±4mm, p=ns). The positive predictive value for predicting incomplete isolation was 65% and the negative predictive value was 83%. CONCLUSION: An identifiable leak between PV and the LBA device seen at the ICUS is predictive of lower PV isolation rates. ICUS may be useful for leak detection to avoid ineffective energy application during circumferential PV ablation. This could also be helpful when other types of energy are used.
| Reference Key |
leite2009arquivosutilidade
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| Authors | ;Luiz Leite;Wilber Su;Susan B. Johnson;Mark Milton;Benhur Henz;Alvaro Sarabanda;Simone N. Santos;Douglas L. Packer |
| Journal | revista cubana de ciencias informáticas |
| Year | 2009 |
| DOI |
10.1590/S0066-782X2009001200017
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