distribution of spontaneous inter-blink interval in repeated measurements with and without topical ocular anesthesia distribuição dos intervalos do piscar espontâneo em medidas repetidas com e sem anestesia tópica ocular

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ID: 139887
2010
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Abstract
PURPOSE: To determine if the distribution of inter-blink time intervals is constant with repeated measurements with and without topical ocular anesthesia. METHODS: Inter-blink time was measured in 15 normal subjects ranging from 19 to 32 years (mean ± SD= 23.9 ± 3.20) with the magnetic search coil technique on 3 different occasions, the last one with topical ocular anesthesia. RESULTS: One-way analysis of variance for repeated measurements showed that topical anesthesia significantly reduced the blink rate (blinks per minute), which was constant in the first two measurements (F=8.27, p=0.0015. First measurement: mean ± SD= 13.7 ± 7.8; second measurement: 13.1 ± 8.5 SD; with topical anesthesia: = 7.2 ± 4.6). However, distributions shape was not affected when the blink rate was reduced. The three distributions followed a Log Normal pattern, which means that the time interval between blinks was symmetrical when the time logarithm was considered. CONCLUSIONS: Topical ocular anesthesia reduces the rate of spontaneous blinking, but does not change the distribution of inter-blink time interval.
OBJETIVOS: Determinar se a distribuição dos intervalos do piscar espontâneo se mantém em medidas repetidas com e sem anesthesia tópica ocular. MÉTODOS: Os intervalos entre movimentos de piscar da pálpebra superior foram medidos com rastreamento magnético (Magnetic Search Coil) em 15 sujeitos (11 do sexo masculino) normais com idades entre 19 a 32 anos (média 23,86 ± 3,20 dp anos). RESULTADOS: Análise de variância unifatorial para medidas repetidas mostrou que a anesthesia tópica ocular diminuiu significativamente a frequência média (número de blinks/minuto) do piscar espontâneo, a qual se manteve constante nas duas primeiras medidas (F=8,27, p=0,0015. Primeira medida 13,7 ± 7,8 DP; segunda medida 13,1 ± 8,5; com anestesia tópica 7,2 ± 4,6). No entanto, a forma da distribuição nas 3 medidas obedeceu uma distribuição do tipo Log Normal, de modo que os intervalos de piscar foram normalmente distribuídos quando o logaritmo do intervalo foi considerado. CONCLUSÕES: A anesthesia tópica ocular diminui significativamente a frequência de piscar, mas não altera a distribuição dos intervalos do piscar espontâneo.
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borges2010arquivosdistribution Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Felipe Placeres Borges;Denny Marcos Garcia;Antonio Augusto Velasco e Cruz
Journal introducing innodb cluster: learning the mysql high availability stack
Year 2010
DOI
10.1590/S0004-27492010000400005
URL
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492010000400005
Keywords
anesthesia anestesia administration topical

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