a patient with a prolonged activated partial thromboplastin time and a deep intracerebral haemorrhage

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ID: 139586
2012
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Abstract
We report on a 57-year-old woman with a pontine haemorrhage and an extremely prolonged activated partial thromboplastin time (aPTT) of more than 240 s, suggestive of a coagulation disorder. Given the location of the haemorrhage, which is associated with a high mortality rate, recombinant factor VIIa was administered, although not all necessary laboratory analyses could be performed at that time. In our case, a deficiency of factor XII was found, which is not associated with an increased bleeding risk. In an acute setting, evaluation of a prolonged aPTT may cause diagnostic and therapeutic challenges, in particular in situations where additional laboratory investigations may not be readily available.
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schindhelm2012casea Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Roger K. Schindhelm;Mariëlle J. Wondergem;Joke Admiraal;Gert Nap;Edwin ten Boekel;Lahcen Hani
Journal journal of neuro-oncology
Year 2012
DOI
10.1159/000342193
URL
http://www.karger.com/Article/FullText/342193
Keywords
diseases of the nervous system

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